产品货号：
Z35367
中文名称：
Nephrin/NPHS1抗体
英文名称：
Anti-Nephrin/NPHS1 Antibody (Clone#OTI1G6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Nephrin/NPHS1 Antibody (Clone#OTI1G6) |
| 指标别名 | NPHS1adhesion molecule;nephrin;CNF;NPHN;nephrin |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | NPHS1 |
| 克隆号 | OTI1G6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1077-1241 of human NPHS1 (NP_004637) produced in E.coli. |
| 实际分子量 | 134.6KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Shipped at -20℃ or with ice packs,Upon delivery store at -20℃.Dilute in PBS(pH7.3) if necessary.Stable for 12 months from date of receipt.Avoid repeated freeze-thaws. |
| 背景资料 | NPHS1,also called Nephrin,it is mapped to 19q13.12.This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney.The gene is primarily expressed in renal tissues,and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes.The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine.A defect in the gene for nephrin,NPHS1,is associated with congenital nephrotic syndrome of the Finnish type and causes massive amounts of protein to be leaked into the urine,orproteinuria.NPHS1 is also required for cardiovascular development. |
| Uniprot ID | O60500 |
| 基因名全称 | nephrosis 1,congenital,Finnish type (nephrin) |
| 蛋白名全称 | Nephrin |
| 推荐稀释比 | Western blot (WB) 1:1000 |
相关搜索：Nephrin/NPHS1抗体，Nephrin抗体，NPHS1单抗，Anti-Nephrin/NPHS1 Antibody (Clone#OTI1G6)